Synergistiq Wellness


A Ptosis Eyelid Treatment without Surgery. Upneeq is the only FDA-approved once-daily prescription eyedrop for acquired ptosis (low-lying lids) that lifts your upper eyelids to open your eyes

How UPNEEQ eyelid treatment Works

Upneeq (oxymetazoline hydrochloride ophthalmic solution), 0.1% is an eye drop that should be inserted once a day, one drop per eye. (Each single-use vial of Upneeq contains enough solution to treat one or both eyes at a time.) Upneeq contains oxymetazoline, an alpha adrenergic agonist that triggers the levator palpebrae muscle (Muller’s or Mueller’s muscle), causing the muscle to contract and raise the upper eyelid.

UPNEEQ eyelid treatment Clinical Data

In clinical studies, the average amount of upper eyelid lift was 1 mm. While this minor lift will not give you the dramatic results possible with surgery, this small lift can be cosmetically and/or medically beneficial to many patients.

Eyelid Treatment
Eyelid Treatment

To learn more about UPNEEQ eyelid treatment, call Synergistiq Wellness today!

Frequently asked questions

How long does Upneeq eyelid treatment last?

Each dose (one drop daily) of Upneeq was shown to be effective for at least 6 hours in clinical studies.

Is Upneeq eyelid treatment FDA-approved to be safe and effective?

Yes, Upneeq is FDA-approved to be both safe and effective for the treatment of acquired eyelid ptosis in adults. To gain FDA approval, Upneeq showed effectiveness in two 6-week trials that followed 304 patients with acquired blepharoptosis. A third study was also conducted to establish that the eye drop is safe.

The main ingredient in Upneeq, oxymetazoline hydrochloride, is the same primary ingredient in decongestant nasal spray, such as Afrin®. In nasal spray, the ingredient works by stimulating the blood vessels to contract, while in Upneeq, this ingredient works to stimulate eyelid muscle contraction.

What are the most common side effects of UPNEEQ eyelid treatment?

The most common adverse reactions with UPNEEQ (occurring in 1-5% of patients) were eye inflammation, eye redness, dry eye, blurred vision, eye pain at time of use, eye irritation, and headache.

How many times a day can I use Upneeq?

Upneeq should only be used as prescribed: one dose, once daily. Work with your doctor to decide how long it is appropriate for you to use Upneeq, and follow their recommendations.

Can I use Upneeq eyelid treatment with my other eye drops?

Yes, you can likely use Upneeq with other eye drops. After using Upneeq, wait 15 minutes before using any other eye drops (or inserting contact lenses). Be sure to talk to your doctor about all of the prescription and over the counter medications and eye drops you use in your consultation to ensure that they are safe to use with Upneeq.

What warnings and precautions are associated with UPNEEQ eyelid treatment?